Full disk or partition encryption is one of the best ways of protecting your data. Not only is each file protected but also the temporary storage that may contain parts of these files is also protected. Full disk encryption will protect all of your files so you don't have to worry about selecting what you want to protect and possibly missing a file.

Red Hat Enterprise Linux 6 natively supports LUKS Encryption. LUKS will bulk encrypt your hard drive partitions so that while your computer is off your data is protected. This will also protect your computer from attackers attempting to use single-user-mode to login to your computer or otherwise gain access.

Full disk encryption solutions like LUKS only protect the data when your computer is off. Once the computer is on and LUKS has decrypted the disk, the files on that disk are available to anyone who would normally have access to them. To protect your files when the computer is on, use full disk encryption in combination with another solution such as file based encryption. Also remember to lock your computer whenever you are away from it. A passphrase protected screen saver set to activate after a few minutes of inactivity is a good way to keep intruders out.