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If the supportsLoadBalancing attribute of the connection factory is set to true then consecutive create connection attempts will round robin between available servers. The first node to try is chosen randomly.
If the supportsFailover attribute of the connection factory is set to true then automatic failover is enabled. This will automatically failover from one server to another, transparently to the user, in case of failure.
If automatic failover is not required or you wish to do manual failover (JBoss MQ style) this can be set to false, and you can supply a standard JMS ExceptionListener on the connection which will be called in case of connection failure. You would then need to manually close the connection, lookup a new connection factory from HA JNDI and recreate the connection.